KPV

Also known as Lys-Pro-Val, α-MSH fragment.

Research / investigational listing only. This compound is not available for consumer purchase from Cellular Sequence and must not be confused with shop products.

Research / investigational compoundThis compound does not have an established approved therapeutic dosing schedule. Doses below describe those reported in published scientific research and should not be interpreted as a treatment recommendation.

At-a-glance profile

Classification: Tripeptide MSH fragment (research / some topical cosmetics elsewhere)
Approval status: Research only · Not approved for human use
Research status: Investigational / reference listing.
Molecular formula: Insufficient reliable evidence identified.
Molecular weight: Insufficient reliable evidence identified.
Sequence: Lys-Pro-Val, C-terminal fragment of α-MSH.
Primary biological target: Insufficient reliable evidence identified.
Half-life: Insufficient reliable evidence identified.
Routes investigated: Insufficient reliable evidence identified.
Human evidence level: D — Primarily animal / preclinical evidence

What is it?

A short melanocortin fragment studied for inflammation models. Injectable research KPV is not an approved medicine and is not sold here. Topical cosmetic use, if any, would be a separate finished product with cosmetic claims only.

Mechanism of action

Proposed melanocortin anti-inflammatory signalling in models.

Not characterised as a registered anti-inflammatory drug.

What is it being studied for?

Experimental gut and skin inflammation models

Investigational findings are not proven clinical benefits unless an authority has labelled that indication.

Evidence level

Overall human evidence grade: D · Primarily animal / preclinical evidence

Human research

Inadequate registration-quality data for drug use.

Preclinical research

Animal, cell and in-vitro findings are listed separately from human effects.

Preclinical inflammation models.

Doses reported in published research

This section does not provide personalised medical dosing. Values are those reported in papers or protocols. Animal mg/kg doses are not converted to human doses.

Doses reported in human studies

Insufficient reliable evidence identified.

Preclinical / animal study dosing

Insufficient reliable evidence identified.

Pharmacokinetics

Reliable human pharmacokinetic data were not identified for this encyclopaedia entry, or are limited to product information for approved presentations.

Safety

Unknown for unregulated injectables.

Unknowns. Absence of a published harm signal is not evidence of safety.

Contraindications. Not for unapproved injection.

Regulatory status

Not approved as a medicine.

Not sold as a research vial. Educational.

Citations

[1] Encyclopaedia note
Encyclopaedia note

For educational and research reference only. This page summarises published scientific literature and does not constitute medical advice, prescribing information or a recommendation to use an investigational compound. Research doses shown describe doses reported in published studies and are not personalised dosing instructions.

Last reviewed 2026-09-13. Research areas: Recovery, Skin & Hair · Compare peptides