Palmitoyl tripeptide-1

Classification

Signal peptide (cosmetic)

Approval status

Cosmetic

Research status

Investigational / reference listing.

Molecular formula

Insufficient reliable evidence identified.

Molecular weight

Insufficient reliable evidence identified.

Sequence

Palmitoylated GHK (Gly-His-Lys) without the copper complex required for GHK-Cu.

Primary biological target

Insufficient reliable evidence identified.

Half-life

Insufficient reliable evidence identified.

Routes investigated

Insufficient reliable evidence identified.

Human evidence level

C — Limited or early human evidence

A cosmetic matrikine used in combination serums (often with palmitoyl tetrapeptide-7 in ‘Matrixyl 3000’ type systems).

Lipidated messenger peptide intended to support the look of dermal matrix proteins.

Topical cosmetic activity only.

• Cosmetic wrinkle appearance

Investigational findings are not proven clinical benefits unless an authority has labelled that indication.

Overall human evidence grade: C · Limited or early human evidence

Cosmetic studies, often combination formulas.

Animal, cell and in-vitro findings are listed separately from human effects.

Fibroblast assays.

This section does not provide personalised medical dosing. Values are those reported in papers or protocols. Animal mg/kg doses are not converted to human doses.

Doses reported in human studies

Insufficient reliable evidence identified.

Preclinical / animal study dosing

Insufficient reliable evidence identified.

Reliable human pharmacokinetic data were not identified for this encyclopaedia entry, or are limited to product information for approved presentations.

Irritation possible.

Unknowns. Absence of a published harm signal is not evidence of safety.

Contraindications. Ingredient allergy.

Cosmetic ingredient.

Cosmetic use. Cellular Sequence offers topical serums, not injectables.

1. [1] Cosmetic matrikine formulations

   Cosmetic matrikine formulations