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Cellular Sequence

Peptide Encyclopaedia

For research purposes onlyResearch onlyNot approved for human use

PNC-27

Research / investigational listing only. This compound is not available for consumer purchase from Cellular Sequence and must not be confused with shop products.

Research / investigational compoundThis compound does not have an established approved therapeutic dosing schedule. Doses below describe those reported in published scientific research and should not be interpreted as a treatment recommendation.

At-a-glance profile

Classification
p53-derived chimeric peptide (research only)
Approval status
Research only · Not approved for human use
Research status
Investigational / reference listing.
Molecular formula
Insufficient reliable evidence identified.
Molecular weight
Insufficient reliable evidence identified.
Sequence
p53 HDM-2 binding region fused to a membrane-penetrating sequence in research descriptions.
Primary biological target
Insufficient reliable evidence identified.
Half-life
Insufficient reliable evidence identified.
Routes investigated
Insufficient reliable evidence identified.
Human evidence level
D — Primarily animal / preclinical evidence

What is it?

Experimental anticancer-concept peptide. Not an approved oncology drug. Not sold. Extremely inappropriate as a wellness vial.

Mechanism of action

Proposed membrane effects on HDM-2-expressing cells in models.

Not a cancer treatment you can buy online.

What is it being studied for?

  • Experimental oncology models

Investigational findings are not proven clinical benefits unless an authority has labelled that indication.

Evidence level

Overall human evidence grade: D · Primarily animal / preclinical evidence

Human research

Not an approved therapy.

Preclinical research

Animal, cell and in-vitro findings are listed separately from human effects.

Controversial/limited literature — not a treatment protocol.

Doses reported in published research

This section does not provide personalised medical dosing. Values are those reported in papers or protocols. Animal mg/kg doses are not converted to human doses.

Doses reported in human studies

Insufficient reliable evidence identified.

Preclinical / animal study dosing

Insufficient reliable evidence identified.

Pharmacokinetics

Reliable human pharmacokinetic data were not identified for this encyclopaedia entry, or are limited to product information for approved presentations.

Safety

Unknown; delay of real oncology care is itself harm.

Unknowns. Absence of a published harm signal is not evidence of safety.

Contraindications. Not for human use.

Regulatory status

Not approved.

Educational warning.

Citations

  1. [1] Encyclopaedia note

    Encyclopaedia note

For educational and research reference only. This page summarises published scientific literature and does not constitute medical advice, prescribing information or a recommendation to use an investigational compound. Research doses shown describe doses reported in published studies and are not personalised dosing instructions.

Last reviewed 2026-09-13. Research areas: Recovery · Compare peptides